| ???£ ESS LTD | Manchester | Skilled Worker | Others | |
| 10architect Ltd | Manchester | Skilled Worker | Architecture | |
| 1D Agency Ltd T/A One Day Agency | MANCHESTER | Skilled Worker | Others | |
| 2030 AUTO CARE LIMITED | Manchester | Skilled Worker | Wholesale & Retail | |
| 24/7 RETAIL LTD | Manchester | Skilled Worker | Others | |
| 24-4 7 FM Limited | Manchester | Skilled Worker | Administrative and support | |
| 247 Wholesale Limited | Manchester | Skilled Worker | Wholesale & Retail | |
| 2CRSi UK LTD | Manchester | Skilled Worker | Others | |
| 2-DTech Ltd. | Manchester | Skilled Worker | Management | |
| 30Seconds Group Ltd | Manchester | Skilled Worker | Others | |
| 360 Alert Security Ltd. | Manchester | Skilled Worker | Others | |
| 3AK (Cheetham Hill) Limited | Manchester | Skilled Worker | Wholesale & Retail | |
| 3AK (MANCHESTER) LIMITED | Manchester | Skilled Worker | Wholesale & Retail | |
| 3VRM Limited | Manchester | Skilled Worker | Computer Programming | |
| 4 Medical Clinical Solution Ltd | Manchester. | Skilled Worker | Social Work | |
| 4 Net Technologies LTD (t/a FourNet) | Manchester | Skilled Worker | Others | |
| 42Gears Mobility Systems (UK) Ltd | Manchester | Global Business Mobility: Senior or Specialist Worker | Computer Programming | |
| 42Gears Mobility Systems (UK) Ltd | Manchester | Skilled Worker | Computer Programming | |
| 42nd Street | Manchester | Skilled Worker | Others | |
| 4Fashions Ltd | Manchester | Skilled Worker | Wholesale & Retail | |
| 4way Consulting Ltd | Manchester | Skilled Worker | Architecture | |
| 5 Health Northwest Ltd T/ A iPharmacy Princess Road | Manchester | Skilled Worker | Others | |
| 5K Records Limited | Manchester | Skilled Worker | Video or Music Production | |
| 7 STAR BLINDS LIMITED | Manchester | Skilled Worker | Others | |
| 7 STAR MERCHANT LTD | MANCHESTER | Skilled Worker | Wholesale & Retail | |